Emile Hirsch as Johnny Truelove

Bruce Willis as Sonny Truelove

Amanda Seyfried as Julie Beckley

Justin Timberlake as Frankie Ballenbacher

Shawn Hatosy as Elvis Schmidt

Ben Foster as Jake Mazursky

Harry Dean Stanton as Cosmo Gadabeeti

Matthew Barry as Interviewer (as Matt Barry)

Fernando Vargas as Tiko "TKO" Martinez

Vincent Kartheiser as Pick Giaimo

Alex Solowitz as Bobby "911"

Alec Vigil as P.J. Truelove

Frank Cassavetes as Adrian Jones

Nicole Dubos as Neighborhood Girl on Couch

Regina Rice as Dance Bitch Girl

Laura Nativo as Party Girl

Amber Heard as Alma

Anton Yelchin as Zack Mazursky

David Thornton as Butch Mazursky

Sharon Stone as Olivia Mazursky

Olivia Wilde as Angela Holden

Heather Wahlquist as Wanda Haynes

Shera Danese as Abby

Nancy De Mayo as Dale Dierker (as Nancy DeMayo)

Xan Cassavetes as Jonna Kirshner

Dominique Swain as Susan Hartunian

Charity Shea as Sabrina Pope

Lukas Haas as Buzz Fecske

Heather Elizabeth Parkhurst as Bartender (as Heather-Elizabeth Parkhurst)

Jesse Erwin as Employee

Paul Johansson as Peter Johansson

Danny A. Abeckaser as Latino Youth (as Danny Abeckaser)

James Molina as Latino Youth (as James A. Molina)

Chuck Pacheco as Chucky Mota

Frank Peluso as Gay "Lumpy" Yeager

Joshua Alba as Klemash

Chris Kinkade as Juergen Ballenbacher

Christopher Rodriguez Marquette as Keith Stratten

Alex Kingston as Tiffany Hartunian

Bobby Cooper as Bob Nolder

Janet Jones as Elaine Holden (as Janet Jones Gretzky)

Alan Thicke as Douglas Holden

Rick Salomon as Salesman

Adrianna Belan as Leigh Fecske

Holt McCallany as Detective Tom Finnegan

Shirley Kurata as Lu

Mario Ardila, Jr. as Santa Fe Kid (uncredited)

Matt Borlenghi as John Kirschner (uncredited)

Curt Clendenin as Bar Patron (uncredited)

Angela Meryl as Party Girl (uncredited)

Bernadette Pérez as Bar Girl (uncredited)

Emilio Roso as Undercover Cop (uncredited)

Kristen Williams as Reporter (uncredited)

Greg Williams as De Rosa

Devin Kamin as Additional VO (uncredited)

Patrick Nguyen as V.C.

Natasha Elliott as Bathroom Party Girl

Stephanie A. Fowler as Delores Stratten (as Stephanie Fowler)

Sadie as Dale Dierker's Dog (uncredited)