Maggie Gyllenhaal as Charlotte Dalrymple

Hugh Dancy as Dr. Mortimer Granville

Jonathan Pryce as Dr. Robert Dalrymple

Felicity Jones as Emily Dalrymple

Rupert Everett as Lord Edmund St. John-Smythe

Ashley Jensen as Fanny

Sheridan Smith as Molly the Lolly

Gemma Jones as Lady St. John-Smythe

Tobias Menzies as Mr. Squyers

Malcolm Rennie as Lord St. John-Smythe

Kim Criswell as Mrs. Castellari

Georgie Glen as Mrs. Parsons

Elisabet Johannesdottir as Mrs. Pearce

Linda Woodhall as Nurse Smalley

Kim Selby as Lady Wheaton

Ann Overstall Comfort as Mrs. Huddleston

John Overstall as Mr. Huddleston

Todd Grinnell as Andy

David Ryall as Judge

Anna Chancellor as Mrs. Bellamy

David Schaal as Tough Guy

Nicholas Woodeson as Dr. Richardson

Ellie Jacob as Nurse