Karen Gillan as Carol Cobb

Iris Apatow as Krystal Kris

Fred Armisen as Darren Eigen

Maria Bakalova as Anika

Vir Das as Ronjon

David Duchovny as Dustin Mulray

Samson Kayo as Bola

Keegan-Michael Key as Sean Knox

Guz Khan as Howie Frangopolous

Leslie Mann as Lauren Van Chance

Kate McKinnon as Paula the Studio Head

Pedro Pascal as Dieter Bravo

Peter Serafinowicz as Gavin

Harry Trevaldwyn as Gunther

Danielle Vitalis as Pippa

Rob Delaney as Carol's Agent, Marti

Raphael Acloque as Zaki

Chris Witaske as Josh

Galen Hopper as Carla

Ross Lee as Mr. Best

Nick Kocher as Scott The EPK Guy

Celeste Dring as Martha the Script Supervisor

Ben Ashenden as Tip the MoCap Guy

Alexander Owen as Cyril the MoCap Guy

Audrina Woolrich as Josh's Daughter

Grant Woolrich as Josh's Son

Grant Fear as Falcon Handler

Maria Bamford as Krystal's Mom

Katie O'Brien as Baltaire Waitress, Monica

Daisy Ridley as Kate

John Lithgow as Tom the Studio Chairman

Austin Ku as Li the Executive Chairman

John Cena as Steve the Stunt Coordinator

Beck as Beck

Donna Air as ET Reporter, Susan Howard

Ivy Wolk as Anti-Krystal YouTuber

James McAvoy as James McAvoy

Kathryn Drysdale as Zaki's Wife, Minnie

Vivian Full as Second ET Reporter

Chloé Delanney as Third ET Reporter