Richard Dreyfuss as Meyer Lansky

Illeana Douglas as Anna Lansky

Anthony LaPaglia as Charlie "Lucky" Luciano

Eric Roberts as Ben "Bugsy" Siegel

Beverly D'Angelo as Teddy Lansky

Yosef Carmon as Rabbi / Caretaker

Mosko Alkalai as Jewelry Shopkeeper

Fima Noveck as Hasid in Grodno

Joshua Praw as Eight-Year-Old Meyer Lansky

Jill Holden as Yetta Lansky

James Harper as Longy Zwillman

Octavia Spencer as Evelyn

Scott Rabinowitz as Zen Ben-Dov

Adam Hendershott as Irish Boy #2

Bernardo Hiller as Max Lansky

Brian Casey as Irish Boy #1

Christopher Rodriguez Marquette as Jake Lansky Ages 9-11

Jeff Perry as American Lawyer

Larry Moss as Benjamin Lansky

Matthew Settle as Bugsy Siegel Ages 17-26

Max Perlich as Meyer Lansky Ages 19-28

Ryan Merriman as Meyer Lansky Ages 12-14

Stanley DeSantis as Arnold Rothstein

Benjamin Kimball Smith as Irish Gang Leader

Anthony Medwetz as Benny Siegel - Age 11

Amit Alon as Boy Outside Jewelry Shop

Paul Sincoff as Charlie Luciano Ages 17-30

P.C. Frieberg as Old City Civilian

Bill Capizzi as Joe 'The Boss' Masseria

Eric Saiet as IRS Man #1

Michael Krawic as IRS Man #2

Brian Frank as Maranzano Deskman

Ron Gilbert as Salvatore Maranzano

David Selburg as Maranzano Bookkeeper

Lawrence Arancio as Buddy's Doctor

Nick Corello as Albert Anastasia

Tom La Grua as Frank Costello

Sal Landi as Joe Adonis

Dean Norris as Naval Captain

Randy Polk as Heavyset Man in Cinema

John Gavigan as Longshoreman

Robert Miano as Vito Genovese

Peggy Jo Jacobs as Virginia Hill

Scott Haven as Flamingo Surveyor

A.J. Tannen as Reporter at LOD Airport

Ron Pacheco as Paul Lansky Age 17

Tom Towles as Henchman at NYC Apartment

Mitchell Roche as Buddy Lansky Age 19

Kenneth Meseroll as FBI Agent at NYC Apartment

Maria Carmen as Conga Dancer

Peter Siragusa as Moe Dalitz

Tom Dreesen as Flamingo Emcee / Eddie Shum

Claudine Barros as Paraguay Stewardess

Angelo Pagán as Asunción Customs Official #1

Jeffrey Sharmat as Buddy Lansky Age 10

Devon Michael as Paul Lansky Age 8

Arnie Alpert as Asunción Customs Official #2

Francis Guinan as Senator Estes Kefauver

Bert Remsen as Senator Tobey

Ron Perkins as Moses Polakoff

Michael Townsend Wright as Jake Lansky

Bix Barnaba as Hallandale Lounge Maitre D'

Maura Vincent as Hallandale Lounge Waitress

Diva Haase as Hallandale Lounge Singer

Michelle Bonilla as Panama Stewardess

Eddie Driscoll as Super Club Maitre d'

Peter Dobson as Man at Supper Club

Raul Guterres as Cuban Revolutionary

Phil Reeves as FBI Agent on Jetliner

Susie Spear Purcell as Female Miami Reporter

Michael Steve Jones as Male Miami Reporter #1

Matthew Butcher as Male Miami Reporter #2

Larkin Campbell as Male Miami Reporter #3

Michael Barrett Caron as Miami Immigration Official #1

Joey Dee as Miami Immigration Official #2

Kathe Mazur as Miami Hospital Nurse

James Noah as Federal Judge

Lynne Marie Stewart as Waitress at Wolfie's

Maury Ginsberg as Uri Behar

Mickey Knox as Older Man at Wolfie's

Scott Brantley as Brazilian Air Passenger

Mário Lara as Panamanian

Douglas M. Nelson as Court Reporter (uncredited)