Richard Dreyfuss as Meyer Lansky

Illeana Douglas as Anna Lansky

Anthony LaPaglia as Charlie "Lucky" Luciano

Eric Roberts as Ben "Bugsy" Siegel

Beverly D'Angelo as Teddy Lansky

Yosef Carmon as Rabbi / Caretaker

Mosko Alkalai as Jewelry Shopkeeper

Fima Noveck as Hasid in Grodno

Joshua Praw as Eight-Year-Old Meyer Lansky

Jill Holden as Yetta Lansky

James Harper as Longy Zwillman

Octavia Spencer as Evelyn

Scott Rabinowitz as Zen Ben-Dov

Adam Hendershott as Irish Boy #2

Bernardo Hiller as Max Lansky

Brian Casey as Irish Boy #1

Christopher Rodriguez Marquette as Jake Lansky Ages 9-11

Jeff Perry as American Lawyer

Larry Moss as Benjamin Lansky

Matthew Settle as Bugsy Siegel Ages 17-26

Max Perlich as Meyer Lansky Ages 19-28

Ryan Merriman as Meyer Lansky Ages 12-14

Stanley DeSantis as Arnold Rothstein