Christina Ricci as Penelope Wilhern

James McAvoy as Johnny/Max

Catherine O'Hara as Jessica Wilhern

Reese Witherspoon as Annie

Peter Dinklage as Lemon

Richard E. Grant as Franklin Wilhern

Simon Woods as Edward Vanderman

Nigel Havers as Mr. Vanderman

Christina Greatrex as Mrs. Vanderman

Michael Feast as Jake/Witch

Ronni Ancona as Wanda

Richard Leaf as Jack the Bartender

Lenny Henry as Krull

Nick Frost as Max

Russell Brand as Sam the Jazz Club Owner

James Howard as Reporter Outside Hospital 1

Paul Viragh as Reporter in Mr. Vanderman's Office

Eve Pearce as Old Lady Card Player

Martin McDougall as Dr. Stone

Burn Gorman as Larry

Simon Chandler as Doctor

Andrew Bailey as Floorman in Card Club

John Voce as Station Cop

Tallulah Evans as Little Girl in Photobooth

Pam Phillips as Old Lady in Photobooth

Shaun Parkes as Reporter Outside Hospital 2

Todd Boyce as Preacher

Matt Rippy as Chauffeur (uncredited)

Preston Nyman as Boy Pupil