Ryu Jun-yeol as Cheon Kyoung-su

Yoo Hai-jin as King Injo

Choi Moo-seong as Lee Hyung-ik

Cho Seong-ha as Lord Choi

Park Myung-hoon as Man-sik

Kim Sung-cheol as Crown Prince Sohyeon

Ahn Eun-jin as Consort Jo

Jo Yoon-seo as Crown Princess Kang

Lee Joo-won as Seok-cheol

Kim Yae-eun as Court Lady Seo

Jung Suk-won as Captain of the guard

Ryu Sung-hyun as Senior physician

Kim Seung-tae as Vassal 1

Shin Mun-sung as Third Royal Secretary

Ahn Seong-bong as Envoy of Qing Dynasty

Moon Seung-bae as Vassal 2

Kim Chae-won as Court Lady Choi

Kim Do-won as Kyoung-jae

Yang Hee-myoung as Physician 1

Kim Sang-Wook as Eunuch

Bae Yong-geun as Herbal Shop Merchant

Jang Tae-min as Doctor

Kim In-kwon as General

Park Hui-eun as Court Lady

Ahn Se-ho as Eunuch

Seo Mun-ho as Lawmaker 3

Ahn Seok-hyun as Prince Soong-seon