Radha Mitchell as Angie

Megan Mullally as Barbie

Catherine Lloyd Burns as Judith

Jacqueline Heinze as Jean

Matt Malloy as Dr. Reiner

Mark Boone Junior as Bill

Louis Ferreira as Russ

Michele Hicks as April

Alan Ruck as Kessel

Octavia Spencer as Nurse B

Vince Vieluf as Jim

Arly Jover as Nurse Edna

Pamela Gordon as Nurse A

John P. Hunter as Hearse Driver

Courtney Watkins as H2O Instructor

Blake Rossi as Michael

Stéphanie Schneider as Party Videographer

Kevin Ratliffe as Simon

Jennie Vaughn as Cashier

Jonathan Slavin as Photo Clerk

Thomas Prisco as Doctor A

Martha Mendoza as Marie

Tom McCleister as Dr. Miller

Garvin Funches as Orderly

Pamela Munro as Loni

Scott Vance as Priest

Henry King as Barbie's Twin

Oliver King as Barbie's Twin

Amy Carlson as Jane

Dakota Leopardi as Justin

Rob Swanson as Man in Park

Roland LaGarde as Mailman

Shelly Desai as Storage Man

Paul Hayes as Dr. Spiegel

Judy Geeson as Angie's Mother