Charlize Theron as Æon Flux

Marton Csokas as Trevor Goodchild

Jonny Lee Miller as Oren Goodchild

Sophie Okonedo as Sithandra

Frances McDormand as Handler

Pete Postlethwaite as Keeper

Amelia Warner as Una Flux

Caroline Chikezie as Freya

Nikolai Kinski as Claudius

Paterson Joseph as Giroux

Yangzom Brauen as Inari

Aoibheann O'Hara as Scientist

Thomas Huber as Scientist

Weijian Liu as Scientist

Maverick Quek as Chemist

Ralph Herforth as Gardener

Megan Gay as Weaver

Rainer Will as Commander Puhl

Charlie Beall as Lieutenant Ord

Bruno Bruni, Jr. as Armory Soldier (as Bruno Bruni)

Ronald Marx as Bregnan Police Captain

Axel Schreiber as Policeman

Katie Mullins as Neighbor

Shaun Lawton as Man in Marketplace

Terry Bartlett as Monican Spy

Betty Okino as Monican Spy

Anatole Taubman as Sasha Prillo's Father

Lavinia Wilson as Sasha Prillo's Mother

Khira Lilli Pobanz as Sasha Prillo (Baby Una)

William Morts as Guard

Phil Hay as Soldier

Nils Dommning as Young Trevor

Bojan Heyn as Young Oren

Justin Schierlo as Boy at Wall

Marianne Sonneck as Boy's Mother

Joost Siedhoff as Crier

Tamara Röhl as Crier

Narges Rashidi as Pregnant Woman

Claas Würfel as Husband

Robin Gooch as Doctor

Anna De Carlo as Bregnan Victim

Martha Fessehatzion as Checkpoint Woman

Milton Welsh as Monican Man

Mehmet Yilmaz as Monican Man

Alex Benjamin as Monorail Passenger

Natacza Boon as Monorail Passenger

Clio Burggraeve as Monorail Passenger

Alexander Flache as Monorail Passenger

Lilja Loeffler as Monorail Passenger

Kim Pfeiffer as Monorail Passenger

Michael Pink as Monorail Passenger

Joachim Schönfeld as Monorail Passenger

Claudine Biswas-MacKenzie as Monorail Passenger (uncredited)

Jannik Büddig as Monorail Passenger (uncredited)

Peggy Flood as Scientist (voice) (uncredited)

Mirko Lang as Monorail Passenger (uncredited)

Mickey Nedimovic as Monorail Passenger (uncredited)

Karolin Oesterling as Monorail Passenger (uncredited)

Wil Röttgen as Man in Museum (uncredited)

Wolfgang Stegemann as Shock Trooper (uncredited)

Stuart Townsend as Monican (uncredited)

Timmi Trinks as Young Bregnaner (uncredited)