Anthony Mackie as Sam Wilson / Captain America

Harrison Ford as President Thaddeus Ross

Danny Ramirez as Joaquin Torres

Shira Haas as Ruth Bat-Seraph

Tim Blake Nelson as Samuel Sterns

Carl Lumbly as Isaiah Bradley

Giancarlo Esposito as Sidewinder

Liv Tyler as Betty Ross

Xosha Roquemore as Leila Taylor

Jóhannes Haukur Jóhannesson as Copperhead

William Mark McCullough as Commander Dennis Dunphy

Takehiro Hira as Prime Minister Ozaki

Harsh Nayyar as Prime Minister Kapur

Rick Espaillat as French President

Todd Allen Durkin as Senior Advisor #1

Dustin Lewis as Senior Advisor #2

Rachael Markarian as President Aide #1

Phuong Kubacki as President Aide #2

Alan Boell as Sergeant Payumo

Ava Hill as Red Hulk Reporter

Marissa Chanel Hampton as Rose Garden Reporter

Katerina Eichenberger as Rose Garden Reporter

Mark Pettit as Rose Garden Reporter

John Mark Bowman as Still Cameraman

Katina Rankin as Hospital Reporter

John Cihangir as Jackal

Eric Mbanda as Whiskey

Koji Nishiyama as Japanese Pilot

David Atkinson as Commander

John Dixon as Ops Specialist

Josh Robin as Josh Robin

Sharon Tazewell as Sharon Tazewell

Pete Burris as Prison Warden

Diesel Madkins as FBI Officer

Matthew Cornwell as Air Force Major

Sandra Aparicio as Nun

Ricky Robles Cruz as Priest

Erika Keck as Female Serpent Mercenary

Hector Banos as Construction Worker

Bill Stinchcomb as Bartender

Gabriela Amarchand as Staff Member

Ariana Lugo as White House Greeter

Ben Vazquez as Bunker Secret Service

Cris Ruiz as Secret Service Agent

Jacqueline Loucks as Secret Service Agent

Jarrett Michael Collins as Armed Soldier

Yaz Takahashi as Japanese Security Head

Tomoko Karina as Ozaki Aide

Robert Tretsch as Murder Victim

Travis Powers as JBAB Guard

Will Holland as Receptionist

Chealon Miller as Surgeon

Trevor Feinstein as Surgeon

Sebastian Stan as Bucky Barnes (uncredited)