Giacomo Gianniotti as Diabolik

Miriam Leone as Eva Kant

Valerio Mastandrea as Ginko

Monica Bellucci as Altea di Vallenberg

Pier Giorgio Bellocchio as Sgt. Palmer

Chiara Martegiani as Elisa Coen

Massimiliano Rossi as Diego Manden

Mario Sgueglia as Emilio

Francesco Turbanti as Loris

Emanuele Linfatti as Martin

Michele Ragno as Vladimiro

Amanda Campana as Giovane truccatrice

Andrea Arru as Diabolik dodicenne

Max Gazzè as Giulio Mondan

Carolina Crescentini as Gabriella Bauer

Paolo Calabresi as King

Lorenzo Zurzolo as Diabolik ventenne

Barbara Bouchet as Contessa Wiendemar

Giacomo Giorgio as Agente Zeman

Paolo Gasparini as Autista di Altea di Vallenberg