Charlie Rowe as Nate Gibson

Marcia Gay Harden as Claire Gibson

Jim Belushi as Dan Gibson

Diane Ladd as Mama Blanche

Josephine Langford as Katy Gibson

Zoe Colletti as Lori

Hannah Riley as Annabelle Gibson

Sasha Compère as Nogo

Olly Sholotan as Benji Betts

Emilio Garcia-Sanchez as Travis Holter

Mishel Prada as Carolyn Alibon

Welker White as Chloe Gaines

Lindsay Ayliffe as Dr. Falerias

Rae Becka as Dr. Steinberg

Sean Hankinson as Dr. Paditar

Pat Dortch as Senator Parsons

Sarah Stouffer as News Reporter

Robert Traveiler as Dr. Clark

Mathew Trent Hunnicutt as Police Officer

Christian Goins as Town Kid

Brian Nguyen as Jay Park

Allie the Monkey as Gigi

Maria Howell as Chairman Filling

Brent Sexton as Sgt. Ellis

J.Stephen Brantley as Dwayne Greeter

Theo Hamm as Leonard

Kathleen Littlefield as Rental Car Clerk

Stephen West-Rogers as Reporter at Grocery Store

Tara Summers as Martha Greeter

Cal Johnson as Uncle Bob

Ava Rose Kinard as College Student

Déjá Dee as Jane Elling

Emmanuel McCord as Young Army Sergeant (as Manny McCord)

Monanik 'Moe' Dugar as Pedestrian

Sam Tan as Nick (protestor)

John Mark Brooks as Hospital Patient

Gillian Rabin as Sophie

Bria Brimmer as Nurse Priscilla

Gary Maniloff as BG - Doctor

Satya Nikhil Polisetti as Dr. Orr

Hunter Gray as Party Guest

Katrina Layman as Flight Attendant (as Katie Layman)

Nic Curtis as Employee

Andrew Dicostanzo as Paul

Katherine Drew as Waitress