Claude Rains as John Jasper

Douglass Montgomery as Neville Landless

Heather Angel as Rosa Bud

David Manners as Edwin Drood

Francis L. Sullivan as Rev. Mr. Septimus Crisparkle

Valerie Hobson as Helena Landless

Zeffie Tilbury as The Opium Woman

Ethel Griffies as Miss Twinkleton

E. E. Clive as Mayor Thomas Sapsea

Walter Kingsford as Hiram Grewgious

Forrester Harvey as Durdles

Veda Buckland as Mrs. Tope

Elsa Buchanan as Mrs. Tisher

George Ernest as Deputy

J.M. Kerrigan as Chief Verger Tope

Walter Brennan as First Gossip