Jonah Hill as Ezra

Lauren London as Amira

Eddie Murphy as Akbar

Julia Louis-Dreyfus as Shelley

Sam Jay as Mo

Nia Long as Fatima

Travis "Taco" Bennett as Omar

David Duchovny as Arnold

Molly Gordon as Liza

Deon Cole as Demetrius

Andrea Savage as Becca

Elliott Gould as Mr. Greenbaum

Rhea Perlman as Bubby

Mike Epps as Uncle EJ

La La Anthony as Shaela

Yung Miami as Tiffany

Khadijah Haqq McCray as Renee

Bryan Greenberg as Issac

Jordan Firstman as Danny

Andrew Schulz as Cousin Avi

Matt Walsh as Don Wood

Emily Arlook as Kim Glassman

Hal Linden as Mr. Greenwald

Winnie Holzman as Mrs. Greenbaum

Richard Benjamin as Dr. Green

Doug Hall as Chris

Anthony Anderson as Barber #1

Malik S. as Patron

Ian Sargent Phillips as Hotel Employee

Ahmad Dugas as Imam

Nelson Franklin as Director

Rob Huebel as Producer

Murray Gray as Maliah

Felipe Esparza as Zminski

Kym Whitley as Aunt Nadine

Doris Hancox as Aunt Donna

Romy Reiner as Jackie Golden

Marla Garlin as Mother

Marcus Mullins as Opposing Teammate

Kash Abdulmalik as Patron #2

Emily G. Miller as Spa Receptionist

Reese Levine as Boy Staring at Ezra

Alana Jackson as Stripper #1

Amy Bernstein as Rabbi #1

Todd Shotz as Rabbi #2

Chayim Frenkel as Cantor

DJ Drama as DJ Drama

Kenya Barris as Airplane Passenger

Robert Diago DoQui as Akbar Photo Double

Chinyere Dobson as Tyra

Pason as Restaurant Guest (uncredited)