Annette Bening as Diana Nyad

Jodie Foster as Bonnie Stoll

Rhys Ifans as John Bartlett

Ethan Jones Romero as Nico

Luke Cosgrove as Luke Tipple

Jeena Yi as Angel Yanigahara

Eric T. Miller as Coach Jack Nelson

Anne Marie Kempf as Candace

Carolyn McCormick as Elise

Marcos Diaz as Dude

Belle Darling as Diana, Age 5

Pearl Darling as Diana, Age 5

Johnny Solo as Aris

Anna Harriette Pittman as Diana, Age 14

Hanler Rodríguez as Miguel

Harraka Eliana as Lucy

Marcella Acuña Báez as Suzanne

Sophia Hernandez as Opposing Girl

Katherine Klosterman as Woman Swimmer

Toussaint Merionne as Taxi Driver

Tisola Logan as Anna

Orpha Salimata as Mia

Erica Cho as Naomi

Marina Vasarhelyi-Chin as St. Maarten Kid #1

James Vasarhelyi-Chin as St. Maarten Kid #2

Nadia Lorencz as Nadia

Marcus Young as Diver

Karly Rothenberg as Dee Brady

Grace Subervi as Medic

Stephen Schnetzer as Commentator

Elizabeth Chahin as Reporter

Garland Scott as Jon Rose

Iván Oleaga as Trainer

Jose Mota Prestol as Fisherman James

Melissa R. Stubbs as Female Cop

Mauricio Adrian as Paramedic (uncredited)

Samantha Gordon as Katie (Register Girl) (uncredited)

Lilo Grunwald as Nina (uncredited)