Maïwenn as Jeanne Du Barry

Johnny Depp as Louis XV

Benjamin Lavernhe as La Borde

Melvil Poupaud as Le Comte Du Barry

Robin Renucci as Monsieur Dumousseaux

Pierre Richard as Le Duc de Richelieu

Marianne Basler as Anne, la mère de Jeanne adolescente

Caroline Chaniolleau as Madame de la Garde

Pascal Greggory as Le Duc D'Aiguillon

India Hair as Adélaïde de France

Suzanne De Baecque as Victoire

Capucine Valmary as Louise

Laura Le Velly as Sophie de France

Patrick d'Assumçao as Choiseul

Diego Le Fur as Le Dauphin

Pauline Pollmann as Marie-Antoinette

Noémie Lvovsky as La Comtesse de Noailles

Micha Lescot as Mercy

Marine Boca as L'amie de Jeanne

Djibril Djimo as Zamor adolescent

Ibrahim Yaffa as Zamor enfant

Thibault Bonenfant as Adolphe à 15 ans

Vincent Colombe as Le gynécologue

Édouard Michelon as L'adjoint du gynécologue

Yann Frisch as Le magicien

Laurent Lévy as Le médecin Le Monnier

Teddy Lussi-Modeste as Le médecin La Martinière

Éric Denize as Le médecin Lorry

Raphaël Quenard as Le Grand Chambellan

Grégoire Oestermann as L'abbé Maudou

Coralie Russier as La sœur de Choisel

Emma Kaboré-Dufour as Jeanne Du Barry enfant

Loli Bahia as Jeanne Du Barry adolescente

Vincent Schmitt as Le Grand Aumonier

Nathalie Richard as Madame de la Roche Fontenille

Gabriel Arbessier as Fils de Madame de la Garde

Guilhem Arbressier as Fils de Madame de la Garde

Aurélie Vérillon as Madame Labille

Laurent Grévill as L'artiste peintre

Bernard Nissile as Le père Gomard

Jürgen Doering as Le styliste

Tom Pécheux as Bossuet, le maquilleur

Manon Rony as Félicité

Alexandre Styker as Édouard, le 1er valet des Mesdames

Jean-Noël Martin as Le prêtre parlant latin

Mattéo Di Capua as Le joueur de violoncelle

Luna Carpiaux as Élisabeth Vigée-Lebrun adolescente

Marie Bokillon as Élisabeth Vigée-Lebrun

Édouard Decker as Le Prince de Ligne

Léa Keiflin as Doublure lumière Jeanne Du Barry

David Decraene as Doublure lumière Louis XV

Owen Rollan as Doublure Zamor enfant

Leeroy Pemsing-Eschylle as Doublure Zamor enfant

Scotty Bernard as Doublure Zamor adolescent

Giovanni Pucci as Adolphe

Stanislas Stanic as Narrator