Gary Cooper as Dr. Corydon M. Wassell

Laraine Day as Madeleine

Signe Hasso as Bettina

Dennis O'Keefe as Benjamin 'Hoppy' Hopkins

Carol Thurston as Tremartini (Three Martini)

Carl Esmond as Lt. Dirk Van Daal

Paul Kelly as Murdock

Elliott Reid as William 'Andy' Anderson

Laurette Luez as Pretty Javanese Girl

Stanley Ridges as Cmdr. William B. 'Bill' Goggins

Renny McEvoy as Johnny Leeweather

Oliver Thorndike as Alabam

Philip Ahn as Ping

Barbara Britton as Ruth

William Severn as Little English Boy (uncredited)

Richard Loo as Chinese Doctor on Train (uncredited)

Douglas Fowley as Bit Part (uncredited)

Ann Doran as Praying Woman (uncredited)

Yvonne De Carlo as Native Girl (uncredited)

Cecil B. DeMille as Voice of Narrator (uncredited)

Irving Bacon as Missionary (uncredited)

Milton Kibbee as 'Janssen' Passenger (uncredited)

Gavin Muir as Dutch Military Messenger (uncredited)

Jack Norton as 'Janssen' Passenger (uncredited)

Philip Van Zandt as Dutch Gunner (uncredited)

Amzie Strickland as Native Woman (uncredited)

George Macready as Dutch Army Captain (uncredited)