Bruce Willis as Eddie 'Hudson Hawk' Hawkins

Danny Aiello as Tommy Five-Tone

Andie MacDowell as Anna Baragli

James Coburn as George Kaplan

Richard E. Grant as Darwin Mayflower

Sandra Bernhard as Minerva Mayflower

David Caruso as Kit Kat

Frank Stallone Jr. as Cesar Mario

Donald Burton as Alfred

Don Harvey as Snickers

Andrew Bryniarski as Butterfinger

Lorraine Toussaint as Almond Joy

Burtt Harris as Gates

Carmine Zozzora as Antony Mario

Stefano Molinari as Leonardo Da Vinci

Enrico Lo Verso as Apprentice

Remo Remotti as Guy on Donkey

Giselda Volodi as Mona Lisa

P. Randall Bowers as Prison Clerk

Arthur M. Wolpinsky as Prison Security Guard

Frank Page as Mario's Driver

Robert Vazquez as Big Stan

Michael Klastorin as Dean

Scott H. Eddo as Jerry

John Savident as Auctioneer

Lisa Matthews as Girl in Car

John Lucantonio as Vatican Guard

Antonino Iuorio as Vatican Guard

Courtenay Semel as Bratty Kid

Massimo Ciprari as The Pope

Douglas Brian Martin as Igg

Steven M. Martin as Ook

Leonardo Cimino as Cardinal

Giangiacomo Colli as Waiter

Frank Welker as Bunny the Dog (voice)

William Conrad as Narrator (voice)