Paul Walker as Chris Johnston

Frances O'Connor as Kate Ericson

Gerard Butler as Andre Marek

Billy Connolly as Professor E.A. Johnston

David Thewlis as Robert Doniger

Anna Friel as Lady Claire

Neal McDonough as Frank Gordon

Matt Craven as Steven Kramer

Ethan Embry as Josh Stern

Michael Sheen as Lord Oliver

Lambert Wilson as Lord Arnaut

Marton Csokas as Sir William De Kere / William Decker

Rossif Sutherland as François Dontelle

David La Haye as Arnaut's Deputy

Steve Kahan as Baker

Christian Tessier as MRI Technician

Marie-Josée Colburn as Oliver's Wife

Richard Zeman as Oliver's Lieutenant

Patrick Sabongui as Jimmy Gomez

Vlasta Vrana as Monk

Cas Anvar as E.R. Doctor

Stephanie Biddle as E.R. Doctor

Amy Sloan as Undergraduate

Ryan Wulff as Undergraduate

Paul Tuerpe as News Reporter

Marian Collier as Archaeologist

Christian Paul as Archaeologist

Edward J. Rosen as Archaeologist

Stephen Liska as ITC Tech

Bruce Ramsay as ITC Tech

Stéfanie Buxton as ITC Tech

Cecile Cristobal as ITC Tech

Richard Donner as Man in Car (uncredited)