Scarlett Johansson as Kelly Jones

Channing Tatum as Cole Davis

Woody Harrelson as Moe Berkus

Ray Romano as Henry Smalls

Jim Rash as Lance Vespertine

Anna Garcia as Ruby Martin

Donald Watkins as Stu Bryce

Noah Robbins as Don Harper

Christian Clemenson as Walter

Colin Woodell as Buzz Aldrin

Nick Dillenburg as Neil Armstrong

Christian Zuber as Michael Collins

Gene Jones as Senator Hopp

Joe Chrest as Senator Vanning

Stephanie Kurtzuba as Jolene Vanning

Colin Jost as Senator Cook

Dariusz Wolski as Edvard

Njema Williams as Wolfie's Joe

Peter Jacobson as Chuck Meadows

Lauren Revard as Ella

Greg Kriek as Henry Look-A-Like

Bill Barrett as Cole Look-A-Like

Gary Weeks as Neil Brown

Todd Allen Durkin as Phil Hunley

Chris Vroman as Zack Tanner

Christian Grey Moore as Kelly’s Photographer

Kade Pittman as Fake Neil

Trevor Morgan as Fake Buzz

Todd James Jackson as Gus Grissom

Peter Wallack as Roger Chaffee

Jeremy Carr as Ed White

Eugene Alper as Nikita Khrushchev

Aidan Patrick Griffin as Yuri Gagarin

Alan Boell as Midtown Bartender

Meg Gillentine as Reporter

Rowan Bousaid as Fuel Engineer

Robert McLeroy as Bryce Firmage

Daniel Norris as Police Officer

Rory Keane as Gantry Engineer

Joseph Britt as Joseph

Frank Hughes as Frank

J. Michael Popovich as Pops

Mark Armstrong as NY Times Reporter

Gerry Griffin as Colonel Taylor

Victor Garber as Senator Hedges (uncredited)

Kyle S. Brown as Secret Service Agent (uncredited)

Robert Tinsley as NASA Employee (uncredited)