Gerard Butler as Will Spann

Jaimie Alexander as Lisa Spann

Russell Hornsby as Detective Paterson

Ethan Embry as Knuckles

Michael Irby as Oscar

Bruce Altman as Barry Adams

Jordan Salloum as Peter

Dani Deetté as Sgt. Andersen

David Kallaway as Frank

Chip Lane as Assistant Deputy

Alphonso A'Qen-Aten Jackson as Larry

Cindy Hogan as Anna Adams

Aleks Alifirenko Jr. as Paranoids

Emily Brinks as Gas Station Girl

Billy Burns as Green Suburban Driver

Robin Fletcher as Secretary

David Gurule as Police Officer

Brice Anthony Heller as Ghost Worker

Samantha Lawless as Additional Voices

Christie McLendon as Police station Receptionist

Alexandra Miles as Paranoid

Robert Walker Branchaud as Jo Paul

Rachel Trautmann as Paranoid

Matthew R. Staley as Drugged Out Guy in Car

David Perez as Hazmat Officer

Grant George as Additional Voices (voice)