Amy Nicholson as Host (Chapter 1: 'Wind') (voice)

Rodney Ascher as Host (Chapter 2: 'Membranes') (voice)

John Waters as Host (Chapter 3: 'Kindred') (voice)

Karyn Kusama as Host (Chapter 4: 'Multitudes') (voice)

Justin Benson as Host (Chapter 5: 'Judy') (voice)

Aaron Moorhead as Host (Chapter 5: 'Judy') (voice)

David Lowery as Host (Chapter 6: 'Dig') (voice)

David Lynch as Self (archive footage)

Jason Stoval as Lounge Wizard (as Sid Pink)

Judy Garland as Various Characters (archive footage)

Jay Leno as Self (archive footage)

Jack Paar as Self / Various Characters (archive footage)

Joaquin Phoenix as Arthur Fleck (archive footage) (uncredited)

Clint Eastwood as Harry (archive footage) (uncredited)

Ray Bolger as Scarecrow (archive footage) (uncredited)

Bert Lahr as Cowardly Lion (archive footage) (uncredited)

Jack Haley as Tin Man (archive footage) (uncredited)

Mark Hamill as Luke Skywalker (archive footage) (uncredited)

Nicolas Cage as Sailor Ripley (archive footage) (uncredited)

Laura Dern as Lula Fortune (archive footage) (uncredited)

Margaret Hamilton as Miss Gulch / Wicked Witch of the West (archive footage) (uncredited)

Patricia Arquette as Renee Madison / Alice Wakefield (archive footage) (uncredited)

Sheryl Lee as The Good Witch (archive footage) (uncredited)

Michael J. Fox as Marty McFly (archive footage) (uncredited)

Crispin Glover as George McFly (archive footage) (uncredited)

Lea Thompson as Lorraine Baines (archive footage) (uncredited)

Thomas F. Wilson as Biff Tannen (archive footage) (uncredited)

Kyle MacLachlan as Paul Atreides (archive footage) (uncredited)

John Hurt as John Merrick (archive footage) (uncredited)

Eddie Murphy as Axel Foley (archive footage) (uncredited)

Paul Hogan as Michael J. 'Crocodile' Dundee (archive footage) (uncredited)

Kirk Douglas as Col. Dax (archive footage) (uncredited)

Tom Cruise as Dr. William Harford (archive footage) (uncredited)

Laurence Fishburne as Morpheus (archive footage) (uncredited)

Keanu Reeves as Neo (archive footage) (uncredited)

Naomi Watts as Betty Elms / Diane Selwyn (archive footage) (uncredited)

Bill Pullman as Fred Madison (archive footage) (uncredited)

Richard Farnsworth as Alvin (archive footage) (uncredited)

Jessica Harper as Suzy Bannion (archive footage) (uncredited)

Willem Dafoe as Bobby Peru (archive footage) (uncredited)

Michael Cera as (archive footage) (uncredited)

Betty Grable as Jill Lynn (archive footage) (uncredited)

Renée Zellweger as Judy Garland (archive footage) (uncredited)

Kathryn Beaumont as Wendy Darling (voice) (archive footage) (uncredited)

Max Records as Max (archive footage) (uncredited)

Catherine O'Hara as Judith (archive footage) (uncredited)

Oakes Fegley as Pete (archive footage) (uncredited)

Tobey Maguire as David (archive footage) (uncredited)

Dickie Jones as Pinocchio (voice) (archive footage) (uncredited)

Alfred Hitchcock as (archive footage) (uncredited)

Denzel Washington as Malcolm X (archive footage) (uncredited)

Holly Hunter as Ada McGrath (archive footage) (uncredited)