Adrien Brody as Jack Starks

Keira Knightley as Jackie Price

Kris Kristofferson as Dr. Thomas Becker

Jennifer Jason Leigh as Dr. Beth Lorenson

Kelly Lynch as Jean Price

Brad Renfro as The Stranger

Daniel Craig as Rudy Mackenzie

Angel Coulby as Intern #2

Steven Mackintosh as Dr. Hopkins

Brendan Coyle as Damon

Mackenzie Phillips as Nurse Harding

Laura Marano as Young Jackie

Jason Lewis as Officer Harrison

Richard Dillane as Captain Medley

Jonah Lotan as Intern #1

Nigel Whitmey as Lieutenant

Ian Porter as Major

Angus MacInnes as Judge

Richard Durden as Dr. Hale

Tristan Gemmill as Officer Nash

Colin Stinton as Jury Foreman

Tara Summers as Nurse Nina

Anthony Edridge as Dr. Morgan (as Antony Edridge)

Teresa Gallagher as Nurse Sally

Paul Birchard as Doctor

Kerry Shale as Prosecutor

Angelo Andreou as Babak/Iraqi Boy

Anne Kidd as State Representative

Charneh Demir as Jamile/Iraqi Mother

Frances Brady-Stewart as Woman with Dog

Lolly Susi as Nurse

Garrick Hagon as Defense Lawyer

Fish as Jimmy Fleisher