Paul Giamatti as Cleveland Heep

Bryce Dallas Howard as Story

Jeffrey Wright as Mr. Dury

Bob Balaban as Harry Farber

Sarita Choudhury as Anna Ran

Cindy Cheung as Young-Soon Choi

M. Night Shyamalan as Vick Ran

Freddy Rodríguez as Reggie

Bill Irwin as Mr. Leeds

Mary Beth Hurt as Mrs. Bell

Noah Gray-Cabey as Joey Dury

Joseph D. Reitman as Long Haired Smoker

Jared Harris as Goatee Smoker

Grant Monohon as Emaciated Smoker

John Boyd as One-Eyebrow Smoker

Ethan Cohn as Glasses Smoker

June Kyoto Lu as Mrs. Choi

Tovah Feldshuh as Mrs. Bubchik

Tom Mardirosian as Mr. Bubchik

Maricruz Hernandez as Perez de la Torre Sister #1

Carla Jimenez as Perez de la Torre Sister #2

Natasha Perez as Perez de la Torre Sister #3

Monique Gabriela Curnen as Perez de la Torre Sister #4

Marilyn Torres as Perez de la Torre Sister #5

George Bass as Mr. Perez de la Torre

Joel Marsh Garland as Pool Guy

James Breen as SPCA Guy

Nell Johnson as Phone Message (voice)

Walter Lafty as Silvertide Band Member

Mark Melchiorre Jr. as Silvertide Band Member

Kevin Frank as Silvertide Band Member

Brian Weaver as Silvertide Band Member

Nick Perri as Silvertide Band Member

Jeremy Howard as Tartutic #1

Brian Steele as Tartutic #2

Kurt Carley as Tartutic #3

Doug Jones as Tartutic #4

David Ogden Stiers as Narrator (uncredited)