Zoe Saldaña as Rita Mora Castro

Karla Sofía Gascón as Emilia Pérez / Manitas del Monte

Selena Gomez as Jessi del Monte

Adriana Paz as Epifanía

Edgar Ramírez as Gustavo Brun

Mark Ivanir as Wasserman

Eduardo Aladro as Berlinger

Emiliano Hasan as Gabriel Mendoza

Gaël Murgia-Fur as Angel

Tirso Pietriga as Diego

Xiomara Ahumada Quito as Woman in Black

Magali Brito as La Ponchis

Jarib dit Javier Zagoya Montiel as Chaplain

Sébastien Fruit as El Flaco

Alejandra Reyes as Rosa / Courtroom Cleaning Lady

Anabel Lopez as Berlinger's Secretary

Daniel Velasco-Acosta as Emilia's Driver

James Gerard as Simon

Braulio Gómez Bernal as TV Anchor

Stéphane Ly-Cuong as Male Surgeon

Tulika Srivastava as Female Surgeon

Johanna Rebolledo Marin as Courtroom Cleaning Lady

Alejandra Díaz Ambrosi as Courtroom Cleaning Lady

Karla Lazo as Courtroom Cleaning Lady

Gabriela Ceceña as Courtroom Cleaning Lady

Lucile Chriqui as Courtroom Cleaning Lady

Sarah Gfeller as Widow

Luis Gabriel Gonzalez as Repented Sicario

Loïc Percheron Lazo as Soloist Child

Rosario Zamora as Chepultepec Cafe Owner

Nathalia Saucedo as Emilia's Maid

Monica Ortiz as Emilia's Maid

Marysol Cordourier as Emilia's Maid

Alonso Venegas-Flores as Reporter

Ana Laura Fortuit as Journalist

Jonas Paz-Benavides as Journalist

Tiphanie Ham as Journalist

Benjamin Díaz Espinoza as Kid on Bike

Holly-Rose Clegg as London Dinner Guest

Kalvin Winson as London Dinner Guest

Lou Justine Moua Nédellec as London Dinner Guest

Michaël Charny as London Dinner Guest

Mohammed Ali Ismail as London Dinner Guest

Katie Valentine as London Dinner Guest

Zelda Rittner as London Dinner Guest

Eric Geynes as London Dinner Guest

Silvia Herraiz as Fundraising Speaker

Ángel Romero as Mariachi

Eduardo Lubo as Mariachi

Manuel Sol Mateo as Mariachi

Théo Guarin as Angel as a Child

Lucas Varoclier as Diego as a Child

Agathe Bokja as Thai Medical Staff (uncredited)

Chun-Ting Lin as Thai Medical Staff (uncredited)

Line Phé as Thai Medical Staff (uncredited)

Paul Kai Te as Sicario (uncredited)

The Rizzler as Emilia Perizz