Aunjanue Ellis-Taylor as Odette Henry

Sanaa Lathan as Barbara Jean Maxberry

Uzo Aduba as Clarice Baker

Mekhi Phifer as James Henry

Julian McMahon as Chick Carlson

Vondie Curtis-Hall as Lester Maxberry

Russell Hornsby as Richmond Baker

Kyanna Simone Simpson as Odette (Young)

Tati Gabrielle as Barbara Jean (Young)

Abigail Achiri as Clarice (Young)

Dijon as James (Young)

Cleveland Berto as Lester (Young)

Ryan Paynter as Chick (Young)

Xavier Mills as Richmond (Young)

Donna Biscoe as Minnie

Tony Winters as Big Earl

Jason Turner as Lil’ Earl

Jalen X. Mason as Young Lil’ Earl

Déjá Dee as Veronica

Renee Harrison as Young Veronica

Jesse Gallegos as Desmond

Craig Tate as Curtis

Angela Davis as Dora

JB Chen as Dr. Li

Zachary Tzegaebge as Adam

Samantha Peel as Loretta

Elizabeth Youman as Beatrice

J. Mardrice Henderson as Daddy 1

Evit Emerson as Daddy 2

Luke Hardeman as Ramsey

Joshua C. Allen as Officer

Sherry Richards as Thelma

Kadianne Whyte as Cherokee

Anita Vereen as Nurse

Christian Haynes as Teen

Andrew Books as Towns person (uncredited)

Robert Fortunato as Officer Nelson (uncredited)

LaFloyd Isiah as Waitstaff (uncredited)

Keeley Kollmann as Symphony Audience (uncredited)

Art Newkirk as Officer Glazier (uncredited)

Micheal J Stiles as Doctor (uncredited)

Dynetta White as Neighbor (uncredited)

Mario White as Dancer (uncredited)