Derek Richardson as Harry Dunne

Eric Christian Olsen as Lloyd Christmas

Mimi Rogers as Mrs. Dunne

Luis Guzmán as Ray

Rachel Nichols as Jessica

Eugene Levy as Principal Collins

Teal Redmann as Terri

Shia LaBeouf as Lewis

Lin Shaye as Margie

Elden Henson as Turk

William Lee Scott as Carl

Michelle Krusiec as Ching Chong

Dana Gould as Mr. Moffitt

Brian Posehn as Store Clerk

Jeff Cesario as P.A. Announcer

Cheri Oteri as Ms. Heller

Bob Saget as Jessica's Dad

Timothy Stack as Doctor

Wayne Federman as Officer Dave

Lucas Gregory as 8-year-old Harry

Holly Towne as Preppy Student

Josh Braaten as Toby

Vahe Manoukian as Security Guard

Carl Mazzocone as Football Coach

Tally Barr as Girl

Lawrence Jordan as Man

Nancy M. Pimental as Museum Director

Julia Duffy as Jessica's Mom

Kevin Centazzo as Boyfriend

Tess Brewer as Little Girl

Jill Talley as Mom

Stacey Hill as Dog Driver

Nathan Wright as Nebbish Guy

Roger Eschbacher as Superintendent Zimmer

Julie Costello as Twin

Shawnie Costello as Twin

Dawn Michelle King as Woman

Colin Ford as Lloyd (at age 5) (uncredited)

Aaron Kaplan as 10-year-old Kid