Dave Goelz as Gonzo / Dr. Bunsen Honeydew / Waldorf / The Birdman (voice)

Steve Whitmire as Kermit the Frog / Rizzo the Rat / Beaker / Cosmic Fish #1 / Rainbow / Miss Piggy (assistant) (voice)

Bill Barretta as Pepe the Prawn / Bobo as Rentro / Johnny Fiama / Bubba the Rat / Cosmic Fish #2 (voice)

Jerry Nelson as Robin / Statler / Ubergonzo (voice)

Brian Henson as Dr. Phil Van Neuter / Sal Minella (voice)

Kevin Clash as Clifford (voice)

Frank Oz as Miss Piggy / Fozzie Bear / Animal / Sam the Eagle (voice)

Jeffrey Tambor as K. Edgar Singer

F. Murray Abraham as Noah

Rob Schneider as TV Producer

Josh Charles as Agent Barker

Ray Liotta as Gate Guard

David Arquette as Dr. Tucker

Andie MacDowell as Shelley Snipes

Kathy Griffin as Female Armed Guard

Pat Hingle as General Luft

Hulk Hogan as Man in Black

Veronica Alicino as TV Stage Manager

David Lenthall as Mikey the Cameraman

Richard Fullerton as Gate Guard

Mark Joy as Gate Guard

Carl Espy as TV Associate Producer

Deron Barnett as Child

Chrissy Mullins as Little Girl

Elaine Nalee as Mashed Potato Lady

Rickey Boyd as Additional Muppet Performer / Animal (assistant) / Beach Hippie

Alice Dinnean as Additional Muppet Performer

John Henson as Additional Muppet Performer / Sweetums

Adam Hunt as Additional Muppet Performer / Scooter (voice)

Peter Linz as Additional Muppet Performer / Miss Piggy (assistant) / Beach Hippie

Drew Massey as Additional Muppet Performer / Beach Hippie

Ed May as Additional Muppet Performer

Andrew Stone as Additional Muppet Performer

Kim Allen as Additional Muppet Performer

Evy Berman as Additional Muppet Performer

John Boone as Additional Muppet Performer

Dennis W. Britt as Additional Muppet Performer

Tyler Bunch as Additional Muppet Performer

Lisa Consolo as Additional Muppet Performer

Rowell Gormon as Additional Muppet Performer

BJ Guyer as Additional Muppet Performer

Greg Jarnigan as Additional Muppet Performer

Rob Killen as Additional Muppet Performer

James J. Kroupa as Additional Muppet Performer

Bruce Lanoil as Additional Muppet Performer

Bob Lynch as Additional Muppet Performer

Pamela O'Conner as Additional Muppet Performer

Tim Parati as Additional Muppet Performer

Thom Stanley as Additional Muppet Performer

Lisa Sturz as Additional Muppet Performer

Mark Sutton as Additional Muppet Performer

Allan Trautman as Additional Muppet Performer

Jay Tyson as Additional Muppet Performer

Gregg Wallace as Additional Muppet Performer

Katie Holmes as Joey Potter (uncredited)

Joshua Jackson as Beach Scene (uncredited)

Gary Owens as UFO Mania Announcer (voice) (uncredited)

Jack Angel as Additional Muppet Performer (uncredited)

Rodger Bumpass as Additional Muppet Performer (uncredited)

Joe Cobb Jr. as M.I.B. Guard (uncredited)

Bill Farmer as Additional Muppet Performer (uncredited)

Langley McArol as Security Guard (uncredited)

Mickie McGowan as Additional Muppet Performer (uncredited)

Phil Proctor as Additional Muppet Performer (uncredited)

John E. Kennedy as Fozzie Bear / Sam the Eagle / Beach Hippie