Andy García as Sgt. John Berlin

Lance Henriksen as Sgt. Freddy Ross

Uma Thurman as Helena Robertson

Graham Beckel as John Taylor

Kathy Baker as Margie Ross

Kevin Conway as Chief Citrine

John Malkovich as Agent St. Anne

Perry Lang as Travis

Nicholas Love as Bisley

Michael O'Neill as Serato

Paul Bates as Venables

Bob Gunton as Goodridge

Lenny Von Dohlen as Michael Blattis

Debbon Ayer as Amanda

Eddie Korbich as Myopic Janitor

Stephen Piemonte II as Trimble

Ken Camroux-Taylor as Pathologist

Carol Schneider as Ann

Deborah Spector as Emerson

Frank Birney as Expert

Mike Winlaw as Male Reporter

Jeffrey Josephson as Popeye

Thomas J. Hageboeck as Max

Jaylene Hamilton as Woman Reporter

Joe Drago as St. Anne's Assistant

Jonas Quastel as Lab Technician

Charles Eaton as Airplane Pilot

Bryan Larkin as Bobby Ross (misspelled as "Bobby Rose" in end credits)