Ezio Greggio as Antonio Motel

Dom DeLuise as Dr. Animal Cannibal Pizza

Billy Zane as Jo Dee Foster

Joanna Pacula as Lily Wine

Charlene Tilton as Jane Wine

Martin Balsam as Det. Martin Balsam

Stuart Pankin as Insp. Pete Putrid

John Astin as The Ranger

Phyllis Diller as Old Secretary

Bubba Smith as Olaf

Larry Storch as Sergeant

Rip Taylor as Mr. Laurel

Shelley Winters as Mrs. Motel (The Mother)

Henry Silva as Police Chief

John Landis as FBI Agent

Joe Dante as Dying Man

John Carpenter as Trenchcoat Man / Gimp

Mel Brooks as Checkout Guest (uncredited)

Marshall Bell as Cross Dressing Agent

Sal Landi as Agent #2

Irwin Keyes as Guard

Kimber Sissons as Push-Up Lady

Eddie Deezen as Video Cameraman

Ken Davitian as Luciano Pavarotti

Peter DeLuise as Checkout Guard

Heather Elizabeth Parkhurst as Beautiful Woman

Jim Maniaci as Rape Culturist #1

Tony Cox as Jail Guard

John Roarke as George H.W. Bush

Wilhelm von Homburg as Maitre 'D