Alex Vincent as Andy Barclay

Brad Dourif as Chucky (voice) / Charles Lee Ray

Catherine Hicks as Karen Barclay

Chris Sarandon as Mike Norris

Dinah Manoff as Maggie Peterson

Tommy Swerdlow as Jack Santos

Jack Colvin as Dr. Ardmore

Neil Giuntoli as Eddie Caputo

Juan Ramírez as Peddler

Alan Wilder as Mr. Criswell

Richard Baird as News Reporter at Toy Store

Ray Oliver as Dr. Death

Aaron Osborne as Orderly

Tyler Hard as Mona

Ted Liss as George

Roslyn Alexander as Lucy

Bo Kane as Male TV Newscaster

Leila Lee Olsen as Female TV Newscaster

Lena Sack as Bellevue Patient

Tommy Gerard as Bellevue Patient

Michael Chavez as Bellevue Patient

Jamie Gray as Bellevue Patient

Erin Munz as Bellevue Patient

Jana Twomey as Bellevue Patient

Suaundra Black as Bellevue Patient

Edan Gross as Friendly Chucky / Kid in Animated Commercial (voice)

John Franklin as Walkabout Chucky (voice)

Michael Patrick Carter as Kid in Animated Commercial (voice)