Brad Dourif as Chucky (voice)

Jennifer Tilly as Tiffany (voice) / Jennifer Tilly

Billy Boyd as Glen / Glenda (voice)

Redman as Redman

Hannah Spearritt as Joan

John Waters as Pete Peters

Keith-Lee Castle as Psychs

Steve West as Stan

Tony Gardner as Tony Gardner

Jason Flemyng as Santa

Nicholas Rowe as Lawyer

Stephanie Chambers as Claudia's Mum

Simon James Morgan as Claudia's Dad

Betty Denville as Claudia

Rebecca Santos as Fulvia

Jordan El-Balawi as Human Glen

Kristina Hewitt as Human Glenda

Daniel Getzoff as Assistant Director

Nicola Mycroft as Reporter

Guy J. Louthan as Don Mancini

Diana Munteanu as Fan

Anouk Diks as Interviewer

Barnaby Harrison as Laughing Puppeteer

Eliot Mathews as Cop #1

Adi Handac as Cop #2

Paul Grossman as Little Boy

Nadia Dina Ariqat as Britney

Rurik Sallé as Journalist (uncredited)