Steve Martin as Peter Sanderson

Queen Latifah as Charlene Morton

Eugene Levy as Howie Rottman

Joan Plowright as Mrs. Virginia Arness

Jean Smart as Kate Sanderson

Kimberly J. Brown as Sarah Sanderson

Angus T. Jones as Georgey Sanderson

Missi Pyle as Ashley

Michael Rosenbaum as Todd Gendler

Betty White as Mrs. Kline

Steve Harris as Widow

Jim Haynie as Ed Tobias

Aengus James as Mike

Jernard Burks as Widow's Bodyguard

Bronzell Miller as Widow's Bodyguard

Matt Lutz as Aaron

Randy Oglesby as FBI Agent

Jesse Corti as Italian FBI Agent

Smalls as Doorman

Victor Webster as Glen

Teddy Lane Jr. as Big Man

Vincent M. Ward as Big Man

Michael Ensign as Daniel Barnes

Tracey Cherelle Jones as Sofia

Josh Waters as College Party Boy

Anne Fletcher as Saleslady

John Prosky as Male Commentator

Alonzo Bodden as Bear

Seth Howard as Caddy

Diana Carreno as Hip Hopper

Tim Stevenson as Hip Hopper

Eddie Garcia as Hip Hopper

Sundy Carter as Flygirl

Anne Bellamy as Hostess

Robin Michelle McClamb as Bartender

Walter Addison as Mr. Kline

Gina Morelli as Rosa

Seth Altschull as Waiter

Deezer D as Heavy Guy

Kelly Price as Nightclub Singer

Candace Jackson as Backup Singer

Erika Nuri as Backup Singer

Faida Amana Brigham as Down Low Dancer

Aminah Abdul-Jillil as Down Low Dancer

Barry Lee Youngblood as Down Low Dancer

Cris Judd as Down Low Dancer

Oscar Orosco as Down Low Dancer

Garland Spencer as Down Low Dancer

Montrose Hagins as Charlene's Neighbor

Laura Grady as Hotel Hostess

Erik Betts as House Guest #4

Christianna Carmine as Club Goer

Wahayn Inello Clayton as Club Goer

Paul Hopkins as Party Guest

Daymond Johnson as Partygoer

Michelle McGinty as Attorney in Photo

Lucas Meyers as Valet

Bibi Nshimba as Club Goer