Jeff Daniels as Bernard Berkman

Laura Linney as Joan Berkman

Jesse Eisenberg as Walt Berkman

Owen Kline as Frank Berkman

William Baldwin as Ivan

Halley Feiffer as Sophie Greenberg

Anna Paquin as Lili

David Benger as Carl

Molly Barton as Graduate Student

Bo Berkman as Graduate Student

Matthew Kaplan as Graduate Student

Simon Kaplan as Graduate Student

Matthew Kirsch as Graduate Student

Daniella Markowicz as Graduate Student

Elizabeth Meriwether as Graduate Student

Ben Schrank as Graduate Student

Amy Srebnick as Graduate Student

Josh Srebnick as Graduate Student

Emma Straub as Graduate Student

Alan Wilkis as Graduate Student

James Hamilton as Man with Joan

Adam Rose as Otto

Henry Glovinsky as Lance

Eli Gelb as Jeffrey

Wayne Lawson as Talent Show Judge

Michael Santiago as Talent Show Judge

Juan Torriente as Talent Show Judge

Patricia Towers as Talent Show Judge

Peggy Gormley as Mrs. Greenberg

Peter Newman as Mr. Greenberg

Greta Kline as Greta Greenberg

Melissa Meyer as Professor

Benjamin Smolen as Student with Puppets

Michael Countryman as Mr. Simic

Alexandra Daddario as Pretty Girl

Nico Baumbach as Jeb Gelber

Maryann Plunkett as Ms. Lemon

Hector Otero as Hector

Ken Leung as School Therapist

Jo Yang as Nurse

Jonathan Baumbach as Man Outside Ms. Lemon's Office (uncredited)

Andrew Kaempfer as Valet (uncredited)

Britta Phillips as Talent Show Audience Member (uncredited)

Bobby Shue as Student (uncredited)

Dean Wareham as Talent Show Audience Member (uncredited)