Humphrey Bogart as Frank McCloud

Edward G. Robinson as Johnny Rocco

Lauren Bacall as Nora Temple

Thomas Gomez as Richard 'Curly' Hoff

Lionel Barrymore as James Temple

Harry Lewis as Edward 'Toots' Bass

Dan Seymour as Angel Garcia

William Haade as Ralph Feeney

Claire Trevor as Gaye Dawn

John Rodney as Deputy Clyde Sawyer

Marc Lawrence as Ziggy

Monte Blue as Sheriff Ben Wade

Rodd Redwing as John Osceola (uncredited)

Jay Silverheels as Tom Osceola (uncredited)

Alberto Morin as Skipper of Rocco's Boat (uncredited)

Pat Flaherty as The Traveler (first Ziggy henchman) (uncredited)

Jerry Jerome as Ziggy's Henchman (uncredited)

John Phillips as Ziggy's Henchman (uncredited)

Beulah Archuletta as Passenger on Bus (uncredited)

John Litel as Dispatcher (uncredited)