Sterling Hayden as Dix Handley

Louis Calhern as Alonzo D. Emmerich

Sam Jaffe as Doc Erwin Riedenschneider

Jean Hagen as Doll Conovan

James Whitmore as Gus Minissi

John McIntire as Police Commissioner Hardy

Marc Lawrence as Cobby

Barry Kelley as Lt. Ditrich

Anthony Caruso as Louis Ciavelli

Marilyn Monroe as Angela Phinlay

Teresa Celli as Maria Ciavelli

William 'Wee Willie' Davis as Timmons

Dorothy Tree as May Emmerich

Brad Dexter as Bob Brannom

John Maxwell as Dr. Swanson

Mary Anderson as Police Broadcaster (voice) (uncredited)

Ray Bennett as Detective in Hardy's Office (uncredited)

David Bond as Father Sortine (uncredited)

Chet Brandenburg as Man at Line-Up (uncredited)

Benny Burt as Taxi Driver (uncredited)

Frank Cady as Night Clerk (uncredited)

Jean Carter as Woman (uncredited)

Mack Chandler as Gambler (uncredited)

David Clarke as Mr. Atkinson (Railroad Man) (uncredited)

John Cliff as Policeman (uncredited)

Harry Cody as Gambler (uncredited)

Gene Coogan as Reporter (uncredited)

Henry Corden as Karl Anton Smith (uncredited)

Chuck Courtney as Red (Boy in Diner) (uncredited)

John Crawford as Reporter (uncredited)

Ralph Dunn as Policeman (uncredited)

Gene Evans as Policeman at Ciavelli's Apartment (uncredited)

Pat Flaherty as Policeman (uncredited)

Alex Gerry as Maxwell (uncredited)

Sol Gorss as Policeman (uncredited)

Fred Graham as Truck Driver (uncredited)

Don Haggerty as Det. Andrews (uncredited)

Eloise Hardt as Vivian (uncredited)

Thomas Browne Henry as James X. Connery (uncredited)

Wesley Hopper as Policeman (uncredited)

George Lynn as Detective at Ciavelli's Apartment (uncredited)

Fred Marlow as Reporter (uncredited)

Strother Martin as William Doldy (uncredited)

Patricia Miller as Girl (uncredited)

Howard M. Mitchell as Secretary (uncredited)

Ralph Montgomery as Counterman (uncredited)

Alberto Morin as Eddie Donato (uncredited)

Kerry O'Day as Girl (uncredited)

Raymond Roe as Tallboy (uncredited)

Henry Rowland as Frank Schurz (Doc's Taxi Driver) (uncredited)

Tim Ryan as Jack (Police Clerk) (uncredited)

James Seay as Officer Janocek (uncredited)

Jack Shea as Policeman (uncredited)

Charles Sherlock as Gambler (uncredited)

J. Lewis Smith as Gambler (uncredited)

J.J. Smith as Police Broadcaster (voice) (uncredited)

Joseph Darr Smith as Reporter (uncredited)

Helene Stanley as Jeannie (Girl in Diner) (uncredited)

Ray Teal as Cop in Car Barn Slugged by Dix (uncredited)

Leah Wakefield as Girl (uncredited)

Harlan Warde as Reporter (uncredited)

Jack Warden as Man (uncredited)

William Washington as Suspect (uncredited)

Constance Weiler as Woman (uncredited)

Judith Wood as Woman (uncredited)

Victor Wood as Evans (uncredited)

Wilson Wood as Man (uncredited)

Jeff York as Policeman (uncredited)