Chevy Chase as Clark Griswold

Beverly D'Angelo as Ellen Griswold

Randy Quaid as Cousin Eddie

Ethan Embry as Russell 'Rusty' Griswold

Marisol Nichols as Audrey Griswold

Miriam Flynn as Cousin Catherine

Shae D'Lyn as Cousin Vicki

Wayne Newton as Himself

Wallace Shawn as Marty

Siegfried Fischbacher as Siegfried

Roy Horn as Roy

Sid Caesar as Mr Ellis

Corinna Harney as Girl at Blackjack Table

Christie Brinkley as Woman in Ferrari

Juliette Brewer as Cousin Ruby Sue

Zachariah Moyes as Cousin Denny

Shannah Laumeister Stern as Mariah

C.C. Costigan as Kelli

Wendy Kaufman as Wendy

Jerry Weintraub as Jilly

Larry Hankin as Preacher

Hayley Mortison as Girl in Hot Tub

Billie Perkins as Casino Guest (uncredited)

Vanessa Bednar as Hot Pool Model (uncredited)

Alana Austin as Tourist (uncredited)

Jeffrey Donovan as Hotel Employee (uncredited)

Sharon Mendel as Paramedic