Rainn Wilson as Randy

Lil Rel Howery as Mike

Aimee Carrero as Jessica

Yvette Nicole Brown as Shanice

Rob Riggle as Dr. Serano

Page Kennedy as Officer Tagert

Xolo Mariduena as Rookie

Eric Jungmann as Nurse Chad

Ayesha Harris as Kim

Luka Jones as Motorcycle Matt

Andy Milder as Bruce

Dalia Rooni as Rachel

Cameron Fuller as Jimmy

Michael J. Sielaff as Johnny

Joaquin Veizaga as Vicente

Liam Oh as Chip (uncredited)