James Stewart as Elwood P. Dowd

Josephine Hull as Veta Louise Simmons

Peggy Dow as Miss Kelly

Charles Drake as Dr. Sanderson

Cecil Kellaway as Dr. Chumley

Victoria Horne as Myrtle Mae Simmons

Jesse White as Wilson

William H. Lynn as Judge Gaffney (as William Lynn)

Wallace Ford as The Taxi Driver

Nana Bryant as Mrs. Hazel Chumley

Grayce Mills as Mrs. Ethel Chauvenet (as Grace Mills)

Clem Bevans as Mr. Herman Shimelplatzer

Harvey as Himself

Don Brodie as Mailman (uncredited)

Pat Flaherty as Policeman (uncredited)

Eula Guy as Mrs. Johnson - Maid (uncredited)

Norman Leavitt as Henry Riley - Cab Driver (uncredited)

Fess Parker as Leslie - Chauffeur (voice) (uncredited)

Maudie Prickett as Elvira - Cook (uncredited)

Dick Wessel as Mr. Cracker (uncredited)