Whoopi Goldberg as Sarah Mathews

Ted Danson as Hal Jackson

Will Smith as Tea Cake Walters

Nia Long as Zora Mathews

Paul Rodríguez as Jose

Jennifer Tilly as Stacy

Peggy Rea as Alberta

Clyde Kusatsu as Bob Takashima

David Bowe as Teddy

Jeffrey Joseph as James

Rawley Valverde as Diego

Fred Mancuso as Bruce

Charlene Fernetz as Paula

Shawn Levy as Dwayne

Lu Leonard as Sperm Bank Nurse

Joe Lerer as Hospital Doctor

Janice Edwards as Hospital Nurse

Michael McFall as Hospital Intern

Phyllis Avery as White Woman #1

Frances Bergen as White Woman #2

O'Neal Compton as Rocky

Michael Halton as Stew

William John Murphy as P.A. #1

Ross Benjamin as P.A. #2

Mel Stewart as Principal Rockwell

David E. Kazanjian as Mr. Alden

Tai the Elephant as Elephant (uncredited)