Don Preston as Self (AKA Dom DeWilde) / Biff Debris / Uncle Meat

Frank Zappa as Self / The Imaginary Director

Phyllis Smith Altenhaus as Self / Sheba Flieschman (as Phyllis Altenhaus)

Dick Barber as Self

Massimo Bassoli as Adult Minnesota Tishman

Rodney Bingenheimer as Self

Jimmy Carl Black as Self

Aynsley Dunbar as Self / Biff Junior

Roy Estrada as Self

Francesca Fisher as The Countess

Bunk Gardner as Self

Buzz Gardner as Self

Lowell George as Self

Dick Kunc as Self

Manfred Lerch as Self

C. Mercedes Lewis as Girl Who Was A Sofa

Sal Lombardo as Self

Meredith Monk as Red Face Girl

Billy Mundi as Rollo

Janet Neville-Ferguson as Self / Market Clerk

Lucy Offerall as Self / Market Clerk (as Miss Lucy)

Fritz Rau as Self

Linda Ronstadt as Self

Carl Schenkel as Self

Cal Schenkel as Self

Stumuk as Elderly Biff Debris

Arthur Dyer Tripp III as Self

Ian Underwood as Self

Haskell Wexler as Self

Tom Wilson as Self

Annie Zannas as Self

Ray Collins as Self / Bill Yurds

Carlo Zappavigna as Young Minnesota Tishman