Natalie Portman as Rifka

Hayden Christensen as Ben

Bradley Cooper as Gus

Ethan Hawke as Writer

Shia LaBeouf as Jacob

Andy García as Garry

Orlando Bloom as David

Chris Cooper as Alex

Anton Yelchin as Boy in the Park

Robin Wright as Anna

Olivia Thirlby as Actress

Maggie Q as Call Girl

Christina Ricci as Camille

Irrfan Khan as Mansukhbhai

Julie Christie as Isabelle

Drea de Matteo as Lydia

Rachel Bilson as Molly

James Caan as Mr. Riccoli, the Pharmacist

Blake Lively as Ex-Girlfriend

John Hurt as Bellhop

Taylor Geare as Teya

Carlos Acosta as Dante

Jacinda Barrett as Maggie

Uğur Yücel as Painter

Shu Qi as Chinese Herbalist

Burt Young as Landlord

Eli Wallach as Abe

Cloris Leachman as Mitzie

Emilie Ohana as Zoe, the Video Artist

Eva Amurri as Sarah

Justin Bartha as Justin, Sarah's Boyfriend

Vedant Gokhale as Pakistani Cab Driver / Painter

Jeff Chena as Bartender

Duane Cooper as Haitian Cab Driver

Abe Karpen as Rifka's Husband

Robert d Scott as Do-Rag

Amy Raudenbush as Mother 1

Elizabeth Hobgood as Mother 2

Jillian Bach as Mother 3

Hiroshi Hsu as Chinese Husband

Richard Cheng as Dry Cleaner

J. Salome Martinez as Nathan's Worker

Clem Moorman as Homeless Man

Rebecca Kaasa as Chic Restaurant Waiter

Dan Ziskie as Party's Guest

Andy Karl as Zoe's Boyfriend