John Cho as Harold Lee

Kal Penn as Kumar Patel

Neil Patrick Harris as Neil Patrick Harris

Rob Corddry as Ron Fox

Jack Conley as Deputy Frye

David Krumholtz as Seth Goldstein

Eddie Kaye Thomas as Rosenberg

Roger Bart as Dr. Jack Beecher

Eric Winter as Colton Graham

Christopher Meloni as Grand Wizard

Danneel Ackles as Vanessa Fanning

Beverly D'Angelo as Sally

Missi Pyle as Raylene

Jon Reep as Raymus

Paula Garcés as Maria

Crystal Mantecon as Venus

Richard Christy as Kenny

Adam Herschman as Archie

Amir Talai as Raza

Ava Knighten Santana as Tammi

Chantel Silvain as Trisha

Echo Valley as Tits Hemingway

Marisa Belinda as Jacuzzi Girl

Claudia Pena as Jacuzzi Girl

Ed Helms as Interpreter

D'Anthony Palms as Light-Skinned Black Security

Mark Muñoz as Cyrus

James Adomian as George W. Bush

Courtney Shay Young as Sparkle

Katheryn Rice as Agnes

Todd Voltz as Travis

Jackson Beals as Carter

Kristen de Nes as Kim

Mark Turner as Joe

Randal Reeder as Big Bob

Errol Sitahal as Dr. Patel

Clyde Kusatsu as Mr. Lee

Mary Deese as Mrs. Lee

Juli Erickson as Old White Woman

Kelvin Payton as Random Passenger

Ron Fagan as Random Passenger

Frank Mondaruli as Head of Security

Lester Speight as Dr. Jonavon White

Hugo Perez as Ramon

Colton Gramm as Groomsman

Patrick Michael Carney as Goon

Jason Konopisos-Alvarez as Goon

Chris Warner as State Trooper

Carsten H.W. Lorenz as Carsten

Angus Sutherland as Anton

Rob Andrist Plourde as Random Amsterdam Stoner

Nicole Graves as Girl at Party (uncredited)

Josh Heald as Terry Air Marshal (uncredited)

Jon Hurwitz as Dancing Devil in Costume Shop (uncredited)

Hayden Schlossberg as Dancing Monkey in Costume Shop (uncredited)

Jimmy Lee Jr. as Terrorist (uncredited)

Krystal Mayo as Raza's Party Guest (uncredited)