Patrick Warburton as Kronk (voice)

Tracey Ullman as Ms. Birdwell (voice)

Eartha Kitt as Yzma (voice)

David Spade as Kuzco (voice)

John Goodman as Pacha (voice)

Wendie Malick as Chicha (voice)

John Mahoney as Papi (voice)

John Fiedler as Rudy (voice)

Jeff Bennett as Additional Voices (voice)

Bob Bergen as Additional Voices (voice)

Brian Cummings as Additional Voices (voice)

Patti Deutsch as Additional Voices (voice)

Anthony Ghannam as Additional Voices (voice)

Jessie Flower as Additional Voices (voice)

Eli Russell Linnetz as Additional Voices (voice)

Mark Lotito as Additional Voices (voice)

Tress MacNeille as Additional Voices (voice)

Travis Oates as Additional Voices (voice)

Grace Rolek as Additional Voices (voice)

Leily Sanchez as Additional Voices (voice)

Ross Simanteris as Additional Voices (voice)

Kath Soucie as Additional Voices (voice)

April Winchell as Additional Voices (voice)

Gatlin Kate James as Additional Voices (voice)