Tracey Ullman as Sylvia Stickles

Johnny Knoxville as Ray Ray Perkins

Selma Blair as Caprice Stickles

Chris Isaak as Vaughn Stickles

Suzanne Shepherd as Big Ethel

Mink Stole as Marge the Neuter

Patricia Hearst as Paige

Jackie Hoffman as Dora

Nicholas E.I. Noble as Weird Paperboy

Lucy Newman-Williams as Neuter Yuppie Woman

Scott Morgan as Neuter Yuppie Man

Wes Johnson as Fat Fuck Frank

David A. Dunham as Mama Bear

David Moretti as Papa Bear

Jeffrey Auerbach as Baby Bear

Susan Allenback as Betty Doggett

Paul DeBoy as Wendell Doggett

Channing Wilroy as Male Motorist

Rosemary Knower as Female Motorist

Jewel Orem as Loose Linda

Richard Pelzman as Paw Paw

Shirleyann Kaladjian as Gay Woman #1

Hari Leigh as Gay Woman #2

Ricki Lake as Self

James Ransone as Dingy Dave

Alan J. Wendl as Officer Alvin

Jonas Grey as Warren the Mailman

Richard DeAngelis as Neuter Man with Sub-Titles

Susan Rome as Messy Melinda

Gwendolyn Briley-Strand as Anti "Oral Sex" Neuter

Kate Kiley as Anti "Bear" Neuter

Grace Nalls as Vaughn's Mother

Ty Ford as Taxi Driver

Randall Boffman as Neuter Businessman

Patsy Grady Abrams as Neuter Old Maid

Doug Roberts as Driving Neuter Husband

Joyce Flick Wendl as Driving Neuter Wife

Jean Schertler as Neuter Grandmother on Bus

Carlos Juan Gonzalez as Bus Driver

Brilane Bowman as Cow Patty

David DeBoy as Dr. Arlington

Kevin Reese as Ronnie the Rimmer

Michael Willis as Tony the Tickler

Lance Baldwin as Larry

Kosha Engler as Lu Ann

Mary Vivian Pearce as Unjudgmental Ex-Sex Addict

Michael Gabel as Mr. Pay Day

John Shields as Chesapeake Cooking Man

Gaelan Connell as Horny Kid

Frederick Strother as "Strange" Sex Addict

Jean Hill as Woman on Fire Escape

Richard Salamanca as Fat Boy A

Britt Prentice as Fat Boy B

Nathan Fulford as Tire Lick Boy

Lynn McCune as Neuter Mom #4

Liam Hughes as Coffee Sex Addict

Steve Mack as Injured Neuter Man #1

Don Hewitt Sr. as Injured Neuter Man #2

Jeanette Chivvis as Fan on Airplane

David Hasselhoff as Self

Bob Adams as Bus Passenger (uncredited)

Michael Ahl as Sex Addict (uncredited)

Tim Caggiano as Disgusted Driver (uncredited)

Angela Calo as Sexaholic Twin (uncredited)

Gino Colbert as Sex Addict (uncredited)

Paul D'Elia as Sex Addict (uncredited)

Clary Davison as Sex Addict (uncredited)

Susan Duvall as Neuter Female Shopper (uncredited)

George Figgs as Neuter (uncredited)

Leanna Foglia as Sexaholic Twin (uncredited)

Rick Kain as Neuter Dad (uncredited)

Mary Lechter as Neuter Mom (uncredited)

Robert Neal Marshall as Croquet Mallet Whacker (uncredited)

Carolyn Rawleigh as Protestor (uncredited)

Leo Rogstad as Convenience Store Sex Addict (uncredited)

Jennifer Rouse as Convenience Store Sex Addict (uncredited)

Thomas W. Stewart as Neuter Husband (uncredited)

Stephen Szibler as Shelf Humping Sex Addict (uncredited)

Michelle Valines as Neuter (uncredited)

Jayson Vance as Big Biker (uncredited)

Craig Wadlin as Sex Addict (uncredited)