Melanie Griffith as Honey Whitlock

Stephen Dorff as Cecil B. Demented

Alicia Witt as Cherish

Adrian Grenier as Lyle

Maggie Gyllenhaal as Raven

Lawrence Gilliard Jr. as Lewis

Jack Noseworthy as Rodney

Michael Shannon as Petie

Harry Dodge as Dinah

Eric Barry as Fidget

Zenzele Uzoma as Chardonnay

Erika Auchterlonie as Pam

Mink Stole as Mrs. Sylvia Mallory

Ricki Lake as Libby

Kevin Nealon as Kevin

Patricia Hearst as Fidget's Mom

Eric Roberts as Honey's Ex

Roseanne Barr as Rosanne

Ray Felton as Roy Stillings

John Michaelson as Charles

Jewel Orem as Maid

Rosemary Knower as Cecil's Mom

Doug Roberts as Cecil's Dad

John Waters as Reporter

Susan Lowe as Family Lady A

Mary Vivian Pearce as Family Lady B

Channing Wilroy as Shop Steward

Patsy Grady Abrams as Family Woman A

Marybeth Wise as A.D

Joe James as Movie Patron (voice, uncredited)

Dan Morgan as Teamster

Delaney Williams as Teamster

Frank Ferrara Sr. as Teamster

Steve Mack as Teamster

Michael Willis as Teamster