Gene Hackman as George Dupler

Barbra Streisand as Cheryl Gibbons

Diane Ladd as Helen Dupler

Dennis Quaid as Freddie Dupler

Kevin Dobson as Bobby Gibbons

William Daniels as Richard H. Copleston

Ann Doran as Grandmother Gibbons

James Nolan as Grandfather Gibbons

Judy Kerr as Joan Gibbons

Marlyn Gates as Jennifer Gibbons

Raleigh Bond as Ultra-Sav Doctor

Mitzi Hoag as Nurse

Charles Siebert as Nevins

James Ingersoll as Hutchinson

Tandy Cronyn as Shuster's Secretary

Len Lawson as Barney

Terry Kiser as Ultra-Sav Day Manager

Vernee Watson-Johnson as Emily

Chris Mulkey as Russell Monk

Steven Peterman as Leon

Richard Stahl as Pharmacist

Faith Minton as Holdup Woman

Jessie Lawrence Ferguson as Jacob Horowitz

Nicholas Mele as Shoplifter

Joe Jacobs as Customer with Violin

Demetre Phillips as Carpenter

Lomax Study as Old Security Guard

Annie Girardot as French Teacher

Bonnie Bartlett as Patricia

Eunice Christopher as Eunice

Virginia Kiser as Virginia

Irene Tedrow as Loft Landlady

Peggy Pope as Waitress

Marilyn Tokuda as Michele Miller

Hamilton Camp as Buggoms

Gary Allen as Desk Clerk

Charles White-Eagle as Gibson Lone Wolf

Adrienne Leonetti as Luigi's Diva

Dominico Sunzeri as Singing Waiter

John Dyar as Singing Waiter

Burc Lander as Singing Waiter

Robin Reed as Singing Waiter

Holly Addy as Pianist

Paul Valentine as Customer

Timothy O'Hagan as Fireman

Tom Regan as Fireman

Kendall McCarthy as Fireman

Gary Reynolds as Fireman

Robert Mitchell as Boys Choir Leader

Kim H. Howard as Holdup Girl (uncredited)