Meryl Streep as Sister Aloysius Beauvier

Philip Seymour Hoffman as Father Brendan Flynn

Amy Adams as Sister James

Viola Davis as Mrs. Miller

Alice Drummond as Sister Veronica

Audrie Neenan as Sister Raymond

Susan Blommaert as Mrs. Carson

Carrie Preston as Christine Hurley

John Costelloe as Warren Hurley

Lloyd Clay Brown as Jimmy Hurley

Joseph Foster as Donald Miller

Bridget Megan Clark as Noreen Horan

Mike Roukis as William London

Frank Shanley as Kevin

Frank Dolce as Ralph

Paulie Litt as Tommy Conroy

Matthew Marvin as Raymond

Molly Chiffer as Sarah

Lydia Jordan as Alice

Suzanne Hevner as Mrs. Kean

Helen Stenborg as Sister Teresa

Tom Toner as Monsignor Benedict

Michael Puzzo as Father Sherman

Margery Beddow as Mrs. Shields

Jack O'Connell as Mr. McGuinn

Marylouise Burke as Mrs. Deakins

Alannah Iacovano as Girl in Church

Valda Setterfield as Parishioner

Gerard Adimando as Parishioner

George Aloi as Parishioner

James P. Anderson as Parishioner

Jackie Brown as Parishioner

Jonathan Castillo as Parishioner

Jennifer Lauren DiBella as Parishioner

Seth Donavan as Parishioner

Brian Hopson as Parishioner

Evan Lewis as Parishioner

Bernadette Lords as Parishioner

Jenny Paul as Parishioner

Robert Shulman as Parishioner

Felicia Tassone as Parishioner

Steph Van Vlack as Parishioner

Robert Ridgell as Organist