Brad Pitt as Sinbad (voice)

Catherine Zeta-Jones as Marina (voice)

Michelle Pfeiffer as Eris (voice)

Joseph Fiennes as Proteus (voice)

Dennis Haysbert as Kale (voice)

Timothy West as Dymas (voice)

Adriano Giannini as Rat (voice)

Raman Hui Shing-Ngai as Jin (voice)

Chung Chan as Li (voice)

Jim Cummings as Luca / Additional Voices (voice)

Conrad Vernon as Jed (voice)

Andrew Birch as Grum / Chum (voice)

Chris Miller as Tower Guard (voice)

Frank Welker as Spike (voice) (uncredited)