Natasha Lyonne as Vivian Abromowitz

Alan Arkin as Murray Samuel Abromowitz

Marisa Tomei as Rita Abromowitz

Eli Marienthal as Rickey Abromowitz

David Krumholtz as Ben Abromowitz

Kevin Corrigan as Eliot Arenson

Jessica Walter as Doris

Mena Suvari as Rachel Hoffman

Carl Reiner as Mickey

Harris Laskawy as Charlie the Cook

Rita Moreno as Belle Abromowitz

Bryna Weiss as Saleslady

Charlotte Stewart as Landlady

Marley McClean as Brooke

Mary Portser as Mrs. Hoffman

Jay Patterson as Dr. Grossman

Natalie Karp as Nurse Curtrell

Jock MacDonald as Man at Brymans

Rich Willis as EMS Guy #1

Armand Reiser as EMS Guy #2

Jack Tracy as Cop #1

Sally Schaub as Waitress

Scotty Atkins as Waiter (uncredited)

Mykal Wayne Williams as Waiter (uncredited)