David Duchovny as Gus

Nicky Katt as Hitler

Catherine Keener as Lee

Mary McCormack as Linda

David Hyde Pierce as Carl

Julia Roberts as Francesca / Catherine

Blair Underwood as Calvin / Nicholas

Enrico Colantoni as Arty / Ed

Erika Alexander as Lucy

Tracy Vilar as Heather

Brandon Keener as Francesca's Assistant

Jeff Garlin as Harvey, probably

David Alan Basche as Nicholas's Agent

Terence Stamp as Man on Plane / Self

Nancy Lenehan as Woman on Plane

Brad Rowe as Sam Osborne

David Fincher as Film Director

Jerry Weintraub as Jerry

Rainn Wilson as First Fired Employee

Eddie McClintock as Second Fired Employee

Dina Spybey-Waters as Third Fired Employee

Sandra Oh as Fourth Fired Employee

Justina Machado as Linda's Friend in Kitchen

Meagen Fay as Diane

Joe Chrest as Sex Shop Man #1

Wayne Pére as Sex Shop Man #2

January Jones as Tracy

Mike Malone as Mike

Anthony Powers as Male Massage Client

Alison Ebbert as Hitler Girlfriend

Jennifer Brusciano as Hitler Hitchhiker

Cole Andersen as Freud

Al Ahlf as Hitler Guard

Lacy Livingston as Miramax Receptionist

Patrick Fischler as Harvey, probably's Assistant

Nathalie Seaver as Clothing Store Owner

Soledad St. Hilaire as Hotel Housekeeper

Roger Garcia as Vampire Neighbor

Laurent Schwaar as Concierge

Dawn Suggs as Hotel Hostess

Charlotte Puckett as Hotel Waitress

Chance Robertson as Biker

Monica Lee Burland as Theater Patron

Kenn Wood as Theater Patron

Cynthia Gibb as Pregnant Woman

Andrew Connolly as Partygoer

Karen Woodley as Partygoer

Chris DeRose as Partygoer

Randy Lowell as Partygoer

Pliny Porter as Partygoer

Coleman Hough as Partygoer

Brad Pitt as Brad Pitt / Self

Karen Grosso as Partygoer (uncredited)

Rashida Jones as Woman (uncredited)

Brian Krow as Bellboy (uncredited)

Steven Soderbergh as Self (uncredited)

Camille Wainwright as Daphne (uncredited)

Tommy Wilson-O'Brien as Fired Employee (uncredited)

Elizabeth Yoder as Hotel Lobby Guest (uncredited)